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KMID : 1191520200250010025
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Journal of Korean Traditional Oncology
2020 Volume.25 No. 1 p.25 ~ p.39
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Effectiveness of acupuncture as an adjunctive therapy for lung cancer: A systematic review and meta-analysis
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Shen Lei
Gwak Si-Ra
Joo Jong-Cheon
Park Soo-Jung
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Abstract
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Objectives : Lung cancer is one of the most common cancer and the leading cause of cancer deaths worldwide. This study aimed to evaluate the role of acupuncture as an adjunctive therapy for lung cancer.
Methods : We conducted a systematic review and meta-analysis on the role of acupuncture therapy in lung cancer treatment by electronic and manual searching in ninedatabases, including PubMed, Cochrane library, Embase, Korean databases, and Chinese medical databases.
Results : A total of 21 trials were included in the meta-analysis. The study results showed that acupuncture therapy had significant efficacy in immuneregulation, including CD3 andCD4. Further analysis revealed that acupuncture therapy significant improvements in quality of life, including Karnofsky performance status(KPS)score, functional assessment of cancer therapy-lung cancer subscale (FACT-L) and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30). In addition, the pooled studies also showed that acupuncture therapy reduced cancer pain and chemotherapy-induced nausea and vomiting.
Conclusions : Our study provides moderate evidence of the efficacy of the acupuncture therapy in the treatment of lung cancer.
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KEYWORD
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Acupuncture, lung cancer, Systematic review, Meta-analysis
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